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A buster is a girl so ugly she makes your eyes hurt and your brain shut off. She looks like she stepped out of a trash can and forgot to brush her teeth.
My cousin's ex is a buster. I saw her once and I ran for my life.
That girl in homeroom is a buster. She looks like a raccoon that got hit by a truck.
I dated a buster once. I still have nightmares about her face.