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A fancy Irish way to call someone a sweetheart, like your mom if she had a bad day and a decent personality.
Hey Macushla, why'd you leave me at the prom with a guy who smells like a dead sock?
Macushla, if you don't text me back, I'm gonna text your ex.
Macushla, you're the only one who can make me laugh when I'm crying over my failed math test.