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You say this when someone is trying to make you care about something you're too lazy or too dumb to care about. It's like telling them to shut up and go away.
'Hey, did you hear about the new pizza place?' 'Gafmenot.'
'You failed math again?' 'Gafmenot. I'm going to fail life, why not?'
'Your dog ate my homework.' 'Gafmenot. My dog's got a better life than you.'