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When some guy or gal gets in the way of two people trying to talk or get busy. They might butt in, stand between them, or act like they're the center of the universe.
My cousin walked into my friend's convo and started talking about his dog like it was the best thing ever.
She sat right between the two guys at the bar and started telling jokes like she was the DJ.
He opened his mouth mid-kiss and started talking about his ex like it was the end of the world.